Parasite Eve II is the sequel to the Sony PlayStation role-playing game Parasite Eve. Parasite Eve II is set several years after the events in the original game. The protagonist from the first game, Aya Brea, also features in this game as the playable character. She becomes involved with another outbreak of Mitochondrial creatures.
Gameplay diverges from the previous game: battles take place in real time and the area of action is less restrictive. The approach is more typical of traditional survival-horror games, although some RPG elements are retained. The game was well-received by the public and achieved high reviewer scores, although it was criticised for using a control system that was seen as being outdated. Unlike the first game, Parasite Eve II was released in Europe as well as Japan and North America.